How TEPEZZA is Given

TEPEZZA is an IV (intravenous) medicine. This means it is delivered through a needle that is placed in your arm. IV medicines like TEPEZZA are most often given by registered nurses (RNs), nurse practitioners (NPs), or another medical professional. The process of delivering an intravenous, or "IV", medicine is called an infusion.

TEPEZZA treatment schedule

Treatment with TEPEZZA is 8 infusions. Each infusion is given 1 time every 3 weeks. That means the full course of treatment with TEPEZZA lasts about 5 months.

TEPEZZA is an IV medicine requiring 8 infusions with 3 weeks between each infusion

Your first and second infusions of TEPEZZA will last about 90 minutes each. Your remaining 6 infusions will take about 60 minutes each, but could be longer depending on how you react to the infusion.

The amount of TEPEZZA that you will receive during each infusion is based on how much you weigh at the time.

Watch real TEPEZZA patients talk about their infusion experience

Karen Video Thumbnail
Read transcript

Karen: I was very scared at the beginning. I was very intimidated by needles but I knew that this was the course of action that I had to take to help me get better.

To avoid everything else that was on the road for me, such as the steroids and the surgery, the infusion didn't sound so bad and I'll be honest with you, my first encounter with the infusion center, I was very nervous when I initially got there. For me, it wasn't such a bad experience and three weeks later, I went back for the second and it was the same thing.

And at that point in time, you're there for a couple of hours so you're starting to talk to the people there. They become your family there. They would make me very comfortable. I didn't even think of it as, "Oh my gosh, I'm sitting here getting an infusion. This is terrible." I thought, "Hey, this isn't bad." They started testing my eyes and they were showing improvement.

INDICATION AND IMPORTANT SAFETY INFORMATION

USE:

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:

  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

Before receiving TEPEZZA, tell your doctor if you:

  • Have inflammatory bowel disease (Crohn’s disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, and dry skin.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please visit TEPEZZA.com for more information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

Read transcript

Jeanne: So I went to my doctor and he told me about TEPEZZA. He told me that it was an infusion, that it was going to be eight infusions over 24 weeks, so once every three weeks. He explained that it's about a two-hour infusion the first time, and the next, subsequent infusions would be about an hour.

I'm a nurse, I do infusions all the time. So I didn't really think it was a big deal, but it was a little scary that I was going put something new into my body. And I was hopeful that it was going to work. So I was elated, I was elated when I got the call that I was going to be able to get TEPEZZA.

The surprise was actually how easy it was to get infused. I think that some people may have an issue, but the nurse started up the infusion and I didn't feel a thing. It was very comfortable, I was sitting in an infusion chair, very private, very comfortable. It was start an IV, get the infusion going, and you're out of the office. It was fabulous. I didn't schedule myself for work that night, and I didn't schedule myself for work the night after because I was thinking, "Okay, I don't know how this is going to go. I don't know if I'm going to have any side effects. Let's see how this works."

And every infusion I had, there was a little improvement with each subsequent infusion. I just found that my eyes were regressing: They weren't as proptotic as they were when I first started. My eyelids became kind of a normal-looking eyelid. I could feel the mobility of my eyes in the eye socket. I could feel less pressure from behind my eyes. They felt lighter. They felt free. And it just felt better and better with each subsequent infusion. It was the best feeling.

It's a hard diagnosis to have, it's hard to live with and to not have the heaviness behind your eyes, to not have the pain behind your eyes, to not have the itchiness, the bulgy red eyes. If I could sum up the entire infusion process in one word or phrase, I think I would say, "Illuminating, it was very illuminating."

INDICATION AND IMPORTANT SAFETY INFORMATION

USE:

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:

  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

Before receiving TEPEZZA, tell your doctor if you:

  • Have inflammatory bowel disease (Crohn’s disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, and dry skin.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please visit TEPEZZA.com for more information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

Where do I go to receive TEPEZZA?

  • On the days you are treated with TEPEZZA, you may visit an infusion center
  • Infusion centers are outpatient clinics that specialize in giving intravenous, or "IV", medicines. A trained medical professional will give you your TEPEZZA and will be with you for the whole process. This person is usually a registered nurse (RN), nurse practitioner (NP), or another medical professional
  • You may also receive TEPEZZA in a hospital or in your doctor's office
  • Sometimes medicines like TEPEZZA can be given by a medical professional in your own home. Check with your doctor and your insurance provider to find out if home infusion is an option for you

    Learn more about home infusion with TEPEZZA:

    Open Email a copy

  • Your insurance provider may assign a location where you’ll get your TEPEZZA or may give you several to choose from. Your doctor may also give you information about where you can get TEPEZZA. Be sure to discuss your options with both your insurance provider and your doctor to find the best location for you
  • If you have been prescribed TEPEZZA and have questions about where you will receive your infusions, you can call Horizon By Your Side, a patient support program, and enroll for assistance. Call 1-833-583-7399, Monday through Friday, 8AM to 8PM ET
Photo of a chair used for infusions Photo of a chair used for infusions Photo of a chair used for infusions

When it comes to treating rare autoimmune diseases like TED, infusion treatments are not uncommon. In fact, infusion treatments are often used for rare autoimmune diseases that you may have heard of, like Guillain-Barre syndrome, Kawasaki disease, myositis, and more.

Why is it important to receive all 8 infusions of TEPEZZA?

  • In a clinical study, more than 8 out of every 10 patients who completed all 8 infusions of TEPEZZA had less eye bulging. Additionally, 7 out of every 10 patients in the clinical studies had improvements in double vision. Patients also had less eye redness, pain, and swelling
  • You may start to see some results with TEPEZZA before all 8 infusions are complete. But to get the full benefits of TEPEZZA treatment, you should finish all infusions as prescribed by your doctor. See before/after photos.
    • It is unknown what the results of TEPEZZA treatment would be without completing all 8 infusions
  • If you’re taking TEPEZZA, get tools and resources to help you continue treatment

Getting ready to start TEPEZZA?

Learn more about preparing for your infusions.

Have questions about TEPEZZA but don’t have a prescription yet?

Call a Nurse Advocate at 1-833-483-7399, Monday through Friday, 8AM to 8PM ET.

Nurse Advocates do not provide individual patient care or medical advice. After speaking with a Nurse Advocate, be sure to talk with your doctor about your treatment options, including TEPEZZA.

USE and IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:
  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

Before receiving TEPEZZA, tell your doctor if you:
  • Have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, and dry skin.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please visit TEPEZZA.com for more information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

USE

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.

USE and IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:
  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

Before receiving TEPEZZA, tell your doctor if you:
  • Have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, and dry skin.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please visit TEPEZZA.com for more information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

USE

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.