How TEPEZZA is Given

TEPEZZA is an IV (intravenous) medicine. This means it is delivered through a needle that is placed in your arm. IV medicines like TEPEZZA are most often given by registered nurses (RNs), nurse practitioners (NPs), or another medical professional. The process of delivering an intravenous, or "IV", medicine is called an infusion.

TEPEZZA treatment schedule

A course of TEPEZZA includes 8 infusions. Each infusion is given 1 time every 3 weeks. That means the full course of treatment with TEPEZZA lasts about 5 months.

TEPEZZA is an IV medicine requiring 8 infusions with 3 weeks between each infusion

Your first and second infusions of TEPEZZA will last about 90 minutes each. Your remaining 6 infusions will take about 60 minutes each, but could be longer depending on how you react to the infusion.

The amount of TEPEZZA that you will receive during each infusion is based on how much you weigh at the time.

Watch Karen W., a real TEPEZZA patient, describe her first infusion experience

Where do I go to receive TEPEZZA?

  • On the days you are treated with TEPEZZA, you may visit an infusion center
  • Infusion centers are outpatient clinics that specialize in giving intravenous, or "IV", medicines. A trained medical professional will give you your TEPEZZA and will be with you for the whole process. This person is usually a registered nurse (RN), nurse practitioner (NP), or another medical professional
  • You may also receive TEPEZZA in a hospital or in your doctor's office
  • Sometimes medicines like TEPEZZA can be given by a medical professional in your own home. Check with your doctor and your insurance provider to find out if home infusion is an option for you

    Learn more about home infusion with TEPEZZA

  • Your insurance provider may assign a location where you’ll get your TEPEZZA or may give you several to choose from. Your doctor may also give you information about where you can get TEPEZZA. Be sure to discuss your options with both your insurance provider and your doctor to find the best location for you
  • If you have questions about where to get TEPEZZA, Horizon Patient Services can help. Just call
    1-833-469-8331, Monday through Friday, 8AM to 8PM ET

Who provides the TEPEZZA treatment?

  • IV treatments like TEPEZZA are most often given by a medical professional, such as a registered nurse (RN) or a nurse practitioner (NP)

Why is it important to receive all 8 infusions of TEPEZZA?

  • In a clinical study, more than 8 out of every 10 patients who completed all 8 infusions of TEPEZZA had less eye bulging. Additionally, 7 out of every 10 patients in the clinical studies had improvements in double vision. Patients also had less eye redness, pain, and swelling
  • You may start to see some results with TEPEZZA before all 8 infusions are complete. But to get the full benefits of TEPEZZA treatment, you should finish all infusions as prescribed by your doctor
    • It is unknown what the results of TEPEZZA treatment would be without completing all 8 infusions

   See before/after photos

Patient Access Managers

When you and your doctor decide on TEPEZZA, you can be paired with a Patient Access Manager (PAM) by calling 1-833-469-8331, Monday through Friday, 8AM to 8PM ET. The PAM provides dedicated, one-on-one support during your treatment journey. They work directly with you to answer non-medical, logistical questions and provide support. They also understand the world of insurance and can help you navigate it. PAMs are dedicated to helping you start and move through treatment with support and care.

Have questions about TEPEZZA but don’t have a prescription yet?

Call a Nurse Advocate at 1-833-483-7399, Monday through Friday, 8AM to 8PM ET.

Nurse Advocates do not provide individual patient care or medical advice. After speaking with a Nurse Advocate, be sure to talk with your doctor about your treatment options, including TEPEZZA.

USE and IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:
  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

Before receiving TEPEZZA, tell your doctor if you:
  • Have inflammatory bowel disease (Crohn’s disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, and dry skin.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please visit TEPEZZA.com for more information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

USE

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.

USE and IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:
  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

Before receiving TEPEZZA, tell your doctor if you:
  • Have inflammatory bowel disease (Crohn’s disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over the counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, and dry skin.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please visit TEPEZZA.com for more information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

USE

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.