TEPEZZA has been proven effective, whether you're newly diagnosed or have had TED for years
Reduce eye bulging and look more like yourself again
In a clinical study OF RECENTLY DIAGNOSED TED PATIENTS*
more than 8 out of 10 people who took TEPEZZA saw reduced eye bulging vs 1 out of 10 people taking placebo†
Individual results may vary.
*24-week clinical trial included 41 patients in the TEPEZZA group who had TED for 9 months or less.
†Eye bulging was reduced by at least 2 mm.
You could see results as early as 6 weeks‡
- With TEPEZZA, some people began to see less eye bulging in as few as 6 weeks, with improvements continuing for the full course of 8 infusions
‡At Week 6, there was an average of -2 mm of reduced proptosis for patients receiving TEPEZZA compared to an average of -0.38 mm reduction for patients receiving placebo.
‡At Week 6, there was an average of -2 mm of reduced proptosis for patients receiving TEPEZZA compared to an average of -0.38 mm reduction for patients receiving placebo.

Real results with TEPEZZA




Real patients with TED less than 9 months who were treated with TEPEZZA in a clinical study. Individual results may vary.

See more clearly by improving double vision
IN CLINICAL STUDIES OF RECENTLY DIAGNOSED TED PATIENTS§
nearly 7 out of 10 people who took TEPEZZA saw improvements in double vision vs 3 out of 10 people taking placebo
Individual results may vary.
§Two 24-week clinical trials included 84 patients in the TEPEZZA group who had TED for 9 months or less.
You could experience relief from double vision
- In those same clinical studies, more than 5 out of 10 people taking TEPEZZA saw their double vision completely go away, versus an average of 2.5 out of 10 people taking placebo

Get multi-symptom relief from eye pain, redness, and swelling. In clinical studies, 2 out of 3 people who completed treatment with TEPEZZA had little to no:

Eye pain
including pain behind the eye and when moving the eye

Redness
of the eye and eyelid

Swelling
of the eye and eyelid
In combined results from two studies, recently diagnosed TED patients’ levels of inflammation were recorded using their Clinical Activity Score (CAS), which is a tool that doctors use to assess their patients’ TED symptoms. It evaluates for the presence of 7 symptoms in the eyes and surrounding area: pain that happens for no apparent reason; pain due to looking at something for too long; eyelid swelling; eyelid redness; redness of the eye itself; swelling of the eye, and inflammation in the inner corner of the eye. The higher the CAS number (from 0 to 7), the more serious the impact of TED is seen to be.
In patients with a CAS of at least 4 at the start of treatment, by the end of treatment 62% (52 of 84) of those treated with TEPEZZA had a CAS of 0 or 1 (seen as inactive disease state) compared to 22% (18 of 87) of those who were treated with placebo.
Each of the 7 symptoms is counted equally toward a single overall score, even though that may not reflect their impact to the individual patient. For example, if a patient has eye redness and eye pain, but is only really bothered by the eye pain, each symptom still adds to the overall score by 1.

Another study shows TEPEZZA is proven to help patients who were diagnosed with TED years ago
In a clinical study of patients who had TED for years
more than 6 out of 10 people who took TEPEZZA saw reduced eye bulging vs 2 out of 10 people taking placebo
Individual results may vary.
Eye bulging was reduced by at least 2 mm.
All patients in the 24-week study had TED for 2 to 10 years, experienced eye bulging, and didn't have symptom changes for at least one year prior.

Real results with TEPEZZA


Real patients with TED less than 9 months who were treated with TEPEZZA in a clinical study. Individual results may vary.
